Survival

Median time to admission or death was greatly improved for Lenus service users in the RECEIVER cohort compared to the control.

Improved probability of admission-free survival was observed through a flattening of the Kaplan-Meier curve in the RECEIVER cohort.

Let's look at what that means when considering how Lenus can transform the traditional COPD pathway.

Evidence

How the Lenus Service has improved survival for users.

24%

12-month mortality rate in control
17%

12-month mortality rate in RECEIVER
155

Days to admission/death in control
335

Days to admission/death in RECEIVER

Chart supplement

More information on the data visualised.

Survival to first admission or death plot
	Control	RECEIVER
n	415	83
Inclusion Criteria	Control cohort criteria	RECEIVER cohort criteria
Event Criteria	The time to a patient's first COPD or respiratory related hospital admission was taken as the 'time to event'. If death occurred before a hospital admission, the date of death was taken instead. In the case that a patient was not admitted or deceased before the data censor date (31/08/2021), 'time to event' was censored on this date.

Study details

ClinicalTrials.gov Identifier: NCT04240353

The feasibility and service adoption observational cohort RECEIVER trial was commenced in September 2019 by NHS Greater Glasgow and Clyde to evaluate the implementation and efficacy of the Lenus COPD Service with high-risk COPD participants matched 1:5 to a control cohort using de-identified contemporary routine clinical data. The protocol is published here with the full results available here.

RECEIVER: Digital Service Model for Chronic Obstructive Pulmonary Disease (COPD)
	Control	RECEIVER
Inclusion Criteria	Selected from the NHS Greater Glasgow and Clyde Safe Haven COPD dataset. Control cohort identification was conducted by iteratively identifying the individuals in the cohort who met the matching criteria for each RECEIVER participant. Duplicate control patients or individuals subsequently onboarded to Lenus COPD were excluded and then the optimal 5 matches for each RECEIVER participant were determined based on closest matches by age. The matching criteria were that matched individuals must: be alive at the onboarding date of the RECEIVER participant, be the same sex as the RECEIVER participant, and have had a COPD or respiratory related admission in the 7 days prior to the RECEIVER participant's onboarding date.	At least one severe COPD exacerbation in the year prior to onboarding to Lenus COPD and/or chronic hypercapnic respiratory failure/sleep disordered breathing requiring NIV/CPAP treatment.
1st Participant Index Date	3rd September 2019
Censor Date	31st August 2021
Total Patients	415	83

NICE advice

Medtech Innovation Briefing

The National Institute of Health and Care Excellence (NICE) has developed a medtech innovation briefing (MIB) on Lenus COPD Support Service for remotely managing chronic obstructive pulmonary disease available here.

Meet our experts

Get in touch if you would like to meet with our product or sales specialists. We'll be pleased to provide solution demonstrations and discuss pricing.

We are a Crown Commercial Service Supplier. Our solutions are on UK frameworks: G-Cloud 13, Spark DPS and AI DPS.