Survival
Outcomes achieved using a digital service model for COPD
Median time to admission or death was greatly improved for Lenus service users in the RECEIVER cohort compared to the control.
Improved probability of admission-free survival was observed through a flattening of the Kaplan-Meier curve in the RECEIVER cohort.
Let's look at what that means when considering how Lenus can transform the traditional COPD pathway.
Evidence
How the Lenus Service has improved survival for users.
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24%
12-month mortality rate in control
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17%
12-month mortality rate in RECEIVER
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155
Days to admission/death in control
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335
Days to admission/death in RECEIVER
Chart supplement
More information on the data visualised.
| Control | RECEIVER | |
|---|---|---|
| n | 415 | 83 |
| Inclusion Criteria | Control cohort criteria | RECEIVER cohort criteria |
| Event Criteria |
The time to a patient's first COPD or respiratory related hospital admission was taken as the 'time to event'. If death occurred before a hospital admission, the date of death was taken instead. In the case that a patient was not admitted or deceased before the data censor date (31/08/2021), 'time to event' was censored on this date. |
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Study details
ClinicalTrials.gov Identifier: NCT04240353
The feasibility and service adoption observational cohort RECEIVER trial was commenced in September 2019 by NHS Greater Glasgow and Clyde to evaluate the implementation and efficacy of the Lenus COPD Service with high-risk COPD participants matched 1:5 to a control cohort using de-identified contemporary routine clinical data. The protocol is published here with the full results available here.
| Control | RECEIVER | |||
|---|---|---|---|---|
| Inclusion Criteria |
Selected from the NHS Greater Glasgow and Clyde Safe Haven COPD dataset. Control cohort identification was conducted by iteratively identifying the individuals in the cohort who met the matching criteria for each RECEIVER participant. Duplicate control patients or individuals subsequently onboarded to Lenus COPD were excluded and then the optimal 5 matches for each RECEIVER participant were determined based on closest matches by age. The matching criteria were that matched individuals must: be alive at the onboarding date of the RECEIVER participant, be the same sex as the RECEIVER participant, and have had a COPD or respiratory related admission in the 7 days prior to the RECEIVER participant's onboarding date. |
At least one severe COPD exacerbation in the year prior to onboarding to Lenus COPD and/or chronic hypercapnic respiratory failure/sleep disordered breathing requiring NIV/CPAP treatment. | ||
| 1st Participant Index Date | 3rd September 2019 | |||
| Censor Date | 31st August 2021 | |||
| Total Patients | 415 | 83 | ||
NICE advice
Medtech Innovation Briefing
The National Institute of Health and Care Excellence (NICE) has developed a medtech innovation briefing (MIB) on Lenus COPD Support Service for remotely managing chronic obstructive pulmonary disease available here.
Get in touch
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