Improved probability of admission-free survival was observed through a flattening of the Kaplan-Meier curve in the RECEIVER group with these participants matched to a control reference population.

12-month admission or death rates and median time to admission or death were also greatly improved for Lenus service users in the RECEIVER cohort compared to the control.

Let's look at what that means when considering how Lenus can transform the traditional COPD pathway.


How the Lenus Service has improved survival for users.

  • 33%

    12-month mortality rate in control

  • 17%

    12-month mortality rate in RECEIVER

  • 40

    Days to admission/death in control

  • 335

    Days to admission/death in RECEIVER

Chart supplement

More information on the data visualised

  Control RECEIVER Dynamic-Scot 1
N 405 83 142
Inclusion Criteria Control cohort criteria RECEIVER cohort criteria Dynamic-Scot 1 cohort criteria
Event Criteria

The time to a patient's first hospital admission was taken as the 'time to event'.

If death occurred before a hospital admission, this was taken instead.

In the case that a patient was not admitted or deceased, 'time to event' was censored at the data censor date (31/08/2021).

Data Censoring

'Time to event' was censored at 600 days.

Dynamic-Scot 1 data did not go beyond 482 days relative to onboarding, hence the early censoring of data.

Study details Identifier: NCT04240353

The feasibility and service adoption observational cohort RECEIVER trial was commenced in September 2019 by NHS Greater Glasgow and Clyde to evaluate the implementation and efficacy of the Lenus COPD Service with high-risk COPD participants matched 1:5 to a control cohort using de-identified contemporary routine clinical data. In March 2021, 'RECEIVER' recruitment was paused and a 'Dynamic-Scot' cohort was established through remote recruitment in the Covid-19 service scale-up to routine care. The protocol is published here with the full results available here.

RECEIVER: Digital Service Model for Chronic Obstructive Pulmonary Disease (COPD)
  Control RECEIVER Dynamic-Scot 1 Service users
Inclusion Criteria

Selected from the NHS Greater Glasgow and Clyde SafeHaven dataset.

Diagnosis of COPD + a COPD-related hospital admission within a 14-day window of a reference RECEIVER trial participant's onboarding date were criteria for entry.

From these criteria, the optimal ~5 matches for each RECEIVER participant were determined based on sex and age whilst excluding duplicate control patients or individuals subsequently onboarded to Lenus COPD.

At least one severe COPD exacerbation in the year prior to onboarding to Lenus COPD and/or chronic hypercapnic respiratory failure/sleep disordered breathing requiring NIV/CPAP treatment. Onboarded at least 365 days before 31/08/2021 (the data censor date for analyses). RECEIVER and Dynamic-Scot 1 participants.
1st Participant Index Date 3rd September 2019 3rd September 2019 15th May 2020 3rd September 2019
Censor Date 31st August 2021
Total Patients 405 83 142 225

NICE advice

Medtech Innovation Briefing

The National Institute of Health and Care Excellence (NICE) has developed a medtech innovation briefing (MIB) on Lenus COPD Support Service for remotely managing chronic obstructive pulmonary disease available here.

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